There’s a new game in town for D2C health business models
When most of us think about direct-to-consumer health care, we think about companies like Hims and Ro selling products (hair loss treatments, erectile dysfunction meds, weight loss treatments, and so on) to their customers, typically pending a consultation with a doctor. What stands out about these companies is their commitment to and ongoing focus on cash pay. If you scroll the websites for any of these players, you can see exactly what it’ll cost.
Per their executives’ statements over the years, it’s unlikely these companies will ever take health insurance. These businesses are committed to that model, and it's working well in areas where speaking to a physician in person is awkward or uncomfortable. There are also clear downsides, like a lack of brand loyalty. Sophisticated consumers can search for the lowest price within a few minutes.

A VC friend recently referred to this set of direct-to-consumer companies as the “shadow healthcare players.” That's spot on because they’re building entirely outside of the system. Because of that, it's possible to be totally upfront about pricing, which, in theory, could drive down costs over time—particularly as we see new entrants like Amazon start to get in on the action.
`Upcoming Sessions
Live conversations with the people shaping healthcare.
Verifying AI in Medicine: Is Healthcare AI Actually Ready for Deployment?
Is AI ready for real-world clinical care? Dr. Zak Kohane and Protege’s Engy Ziedan debate what it takes to safely trust AI in diagnosis and treatment, from benchmark performance and clinical evidence to whether we’re holding AI to a higher standard than humans.
Why Are Hospitals Hiring Chief AI Officers?
As AI moves from pilots into day-to-day healthcare operations, health systems are having to decide who should actually own the
Where are AI Agents Actually Working in Healthcare, and Why?
While the healthcare industry remains locked in a high-level debate over the theoretical potential of artificial intelligence, a select group of
Top Employers Share What Healthcare Startups Need to Know in 2026
As enterprise health purchasers face volatile medical cost trends and tightening operational margins, the standard vendor pitch of "improved clinical efficiency&
Peptide Therapy: Where Do We Go From Here?
Watch the full webinar Peptide therapies have moved from niche biohacking circles into mainstream medicine, reshaping conversations around weight management, metabolic health,
Not everyone can access the top 1% of physicians. Will AI change that?
Historically, top-tier medical expertise was limited by wealth and geography. As AI reshapes healthcare delivery, a vital question emerges: can it democratize intelligence to give everyone access to the caliber of care typically reserved for the top 1%?
Privacy AI and the Future of HIPAA
Watch the Full Webinar As AI reshapes healthcare and more patient data flows beyond traditional clinical settings, the rules governing privacy, access,
What will AI do for employer healthcare and benefits?
Employer healthcare may be one of the most practical — and overlooked — proving grounds for AI.
Hospitals as the new go-to-market, lessons from the trenches
Watch the Full Webinar Health systems are entering a new frontier, one where innovation isn’t optional, and meaningful change requires creativity,